Mastalgia. The prevalence of cyclical mastalgia and its association with mammography replicate clinic-based findings. For claims with a date of service on or after October 1, 2015, use an equivalent ICD-10-CM code (or codes). Of the 236 patients, 10 women had cyclical breast pain, 116 had noncyclical, nonfocal breast pain, and 110 had noncyclical, focal breast pain. A non-neoplastic or neoplastic disorder that affects the breast. Previous Term: Mast Cell. 16). Patients with a mild degree of pain (visual analogue pain score (VAS) < 3 on a score of 0 to 10) are. ICD-9-CM 611. 1007/BF03350214 Corpus ID: 35007507; Hormonal profile in benign breast disease. This type of breast pain lines up with your menstrual cycle. 4 - other international versions of ICD-10 M77. Young women (< or = 35 years) were more than three times as likely to have had a mammogram (75%) if they regularly experienced cyclical mastalgia than if they did not (24%; p < 0. 2% (n = 85) with reassurance. Asthma is a Mastalgia is considered the most common benign breast disorder in women during the fertile period by a prevalence rate of about 65% [1–3]. 4 Mastodynia. Geschickter CF. Mastalgia is a common condition in women of reproductive years. Cyclical breast pain is related to the menstrual cycle. Mastalgia frequency was monthly in all of the cyclic mastalgia patients. In clinical practice this phenomenon became known as cyclic mastalgia. She enters her menstrual experience on a separate part of chart, which allows us to visualize the full month's pain severity in an uncluttered. 7 Day Meal Plan & Recipe Guide. 175 patients (83%) responded, with an. - begins in luteal phase of menstrual cycle and subsides with menses; - usually bilateral; - poorly localized; - associated with outer quadrants; Cyclic mastalgia is characterized as. Cyclical mastalgia is a common problem sometimes severe enough to interfere with normal activity levels, and it is related to excessive use of mammography among young women. Analyses were performed using STATA 10 (StataCorp. Mastalgia is the most common breast symptom in patients attending a breast clinic []. In previous studies which were conducted to evaluate the effect of flaxseed on cyclic mastalgia, a specific amount of flaxseed powder (25–30 g/d) was administered for patients [6, 19, 20]. , 4 there are difficulties in accepting the organic explanation as the entire explanation for the syndrome. Breast pain is divided into two basic groups. For patients who present with breast pain, the first-line options are reassurance, lifestyle changes including the avoidance of caffeine-containing food and beverages, use of a supportive bra, and modification of hormone replacement therapy. The 2024 edition of ICD-10-CM N61. 71 • ICD-10 code: N64. Occurs monthly. It is not expensive and can be tried for two or three months to see if there is any benefit. Vitamin E (with or without mefenamic acid), could reduce the intensity of pain about 7% (95% CI: 2-30%). The Mean age ± SD in women with cyclic mastalgia and control were (28. 4103/1735-9066. • mastalgia, mastodynia, or breast tenderness is a common problem experienced by most women. 4 became effective on October 1, 2023. Pain in the breast generally classified as cyclical (associated with menstrual. 22 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Cyclic vomiting syndrome (CVS) consists of recurrent paroxysms of severe nausea and vomiting separated by symptom free periods. 4. Association of Selected Risk Factors with Mastalgia Cases According to the prevalence of various risk factors among mastalgia cases and considering 50% prevalence as average mastalgia. 9 - other international versions of ICD-10 N64. It is possible that other foreign versions of ICD-10 N62. Terdapat tiga jenis nyeri payudara, yaitu nyeri payudara siklik, nonsiklik, dan nyeri payudara extramammary. doi: 10. It affects roughly 70% of women at some point in their life. Breast pain, also known as mastalgia, mastodynia, and mammalgia, is mild to intense pain in one or both breasts. 9 may differ. Published in British medical journal 29 November 1975. two thirds of women with mastalgia have cyclical pain and the remaining third have pain which is non-cyclical. A Canadian double-blind, placebo-controlled study indicated notable improvement in a group of women with severe cyclical breast pain after they incorporated 25 grams of dietary flaxseed into their daily diets. Mastodynia. Treating cyclical and non-cyclical breast pain If any treatment is needed, the options for treating cyclical and non-cyclical pain are often the same. Using systematic review and meta‑analysis, this study aimed to determine the effect of vitamin E on ameliorating the intensity of pain of primary. Ninety-three patients with severe cyclical mastalgia of more than 6 months. This type of pain usually occurs in both breasts. Dan adanya kondisi ini biasanya akan membuat seorang wanita merasa nyeri yang panas dan menusuk yang diikuti dengan dada yang terasa sesak. The prevalence of cyclical mastalgia and its association with mammography replicate clinic-based findings. Breast pain can range from mild to severe. Mastalgia, mastodynia, or breast tenderness is a common problem experienced by most women. Intervention: Each of the Nigella sativa seed oil, diclofenac and placebo gels is separately applied 2 times daily to the site of breast pain in a group of 50 women with cyclic mastalgia. 4 Mastodynia. Berikut ini penjelasannya: 1. Some women's breasts are unusually tender and lumpy, with symptoms of pain and dull heaviness that vary with the menstrual cycle. 9 With a different volume of secretion produced during the luteal phase. Cyclical mastalgia ICD-10 code N64. doi: 10. 27% of multipl e fibroadenoma, 12. Sangat jarang kasus mastalgia berhubungan dengan kanker. In the patients the severity of pain may adversely impact the routine life. Integrated yoga. The breasts may be described as "lumpy" or "doughy". Mastalgia. 3% with cyclical nodularity, 6. The diagnosis codes found in the Tabular List and Alphabetic Index have been adopted under HIPAA for all healthcare settings. 1, 2 It can be sub-categorized as cyclic, non-cyclic and extra-mammary pain according to different onset time and area, with the first two types referred to as true mastalgia. 6%, and 22 women developed breast cancer. However, diffuse bilateral pain is very common in women. During a period, the. Breast pain that is associated with the menstrual cycle due to hormonal variation often associated with breast. 2 ± 10. Semantic Scholar extracted view of "Tamoxifen therapy for cyclical mastalgia: dose. There are a number of causes including infection and benign (non-cancerous) breast lumps. There are a number of causes including infection and benign (non-cancerous) breast lumps. N61. 4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. On fifth and sixth visit, 46 patients reported with pain score 0, one with pain score of 2 and four with pain score of 6. While some women experience a general breast tenderness that seems to linger, others can experience extreme pain from the slightest touch. Careful examination can differentiate chest wall pain from true breast pain. Among the mastalgia cases, among the various clinical risk factors, H/O Mastalgia was the most prevalent (38%) followed by the Cyclical mastalgia (33%). Visscher DW, Nassar A, Degnim AC, et al. Mastalgia pain is mostly mild, but some patients describe moderate or severe pain . P. Tends to occur in both breasts, and sometimes the associated armpits and arms. Benign breast disease in women is a very common finding and results in a diagnosis in approximately one million women annually in the United States (1). Approximately 8-10% of premenopausal women experience moderate to severe perimenstrual breast pain or cyclical mastalgia, monthly. Cyclic mastalgia is introduced as a part of the premenstrual syndrome and two thirds of mastalgia is of this type that often occurs in the luteal phase of menstrual cycle. In randomized trials conducted in Great Britain, 4 58 percent of women with cyclic mastalgia and 38 percent of those with noncyclic mastalgia responded to treatment with evening primrose oil (γ. 2007. 2021 - New Code 2022 2023 2024 Billable/Specific Code. Most premenopausal women experience some degree of discomfort, ranging from 2–3 days premenstrual tenderness to severe pain affecting their quality of life. Results: Seventy-nine percent reported having regularly experienced cyclical breast symptoms; 48% have asked a health care provider about their mastalgia. Mastalgia ICD-10-CM Alphabetical Index. Up to 7 in 10 women develop breast pain (mastalgia) at some stage in their lives. She enters her menstrual experience on a separate part of chart, which allows us to visualize the full month's pain severity in an uncluttered. There are a number of causes including infection and benign (non-cancerous) breast lumps. The 2024 edition of ICD-10-CM M83. 2021; 4 (1): p. Hershey Medical Center, 30 Hope Drive, Suite 1800, Mail Code EC 008, Hershey, PA 17033-0859. A randomized, double‐blind, placebo‐controlled, multicenter clinical trial was conducted with 111 otherwise healthy euthyroid women with a history of breast pain and all doses were associated with an acceptable safety profile. medial. Mastalgia during at least 5 days of the cycle before the treatment was the strict inclusion condition. Results from two-sample t-test showed a nonsignificant decrease in cyclical mastalgia individually for the three treatment groups compared with the placebo group (EPO, p=0. Breast pain is a common symptom in most women during their lifetime, and many times is self-limited. A lady health worker provides the lady with explanation about filling the chart (Fig. Some people begin to have cyclic pain around the time of ovulation, continuing until the start of their menstrual period. According to PSQI global score, overall sleep quality was significantly lower in the NCBP group compared to the control group (p. ICD-10 code lookup — find diagnosis codes (ICD-10-CM) and procedure codes (ICD-10-PCS) by disease, condition or ICD-10 code. The breasts are often painful, tender, and swollen at this time, but symptoms improve at other points in the cycle. It accounts for two-thirds of women with breast pain, of which two-thirds have interference in their daily activities []. About one third of women with mastalgia have this. Recent population based 9 , and breast clinic-based 10 , 11 studies suggest that up to 70% of women under 55 experience breast pain. The early onset mastalgia in this study requires further exploration for determination of its risk factors. The selective estrogen-receptor modulator tamoxifen is most widely known and used for its role in the adjuvant treatment of breast cancer, but it has also been studied for the management of breast pain at a dose of 10 to 20 mg daily. Saat menjelang haid hingga menstruasi, tubuh wanita mengalami perubahan hormon. 2 The former is assumed to be due to. Existing systematic reviews discuss dated treatment options that provide limited symptomatic. Usually starts during the luteal phase of the cycle (within 2 weeks before. Sclerosing adenosis and risk of breast cancer. Complaints of mastalgia are more common in premenopausal women. Heavy breasts. 4 ICD-10 code description Mastodynia Primary outcomes 1 Description severity of cyclic breast pain Timepoint at the begining of the study- at the end of first cycle of intervention- at the end of the second sycle of intervention Method of measurement visual analog scale 2 Description duration of the breast pain. @article{Pruthi2010VitaminEA, title={Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. ICD-10-CM Coding Rules. 2007;23(01):10–13 A clinically useful response was observed in 76% cyclical mastalgia and in 36% of those with noncyclical mastalgia treated with danazol, and in 55% of the patients with cyclical mastalgia and in 33% for those with noncyclical mastalgia treated with evening primrose oil. 3 versus 33. There is often a prodromal phase of nausea and pallor. Symptom control is the mainstay of treatment. Ductal ectasia, when the ducts of the breast dilate, may also lead to breast pain on one side. Cyclic mastalgia is defined as breast pain of moderate-to-severe intensity, lasting ≥7 days and, because it demonstrates a relationship to the menstrual cycle, occurring in premenopausal women . Cyclic Mastalgia (Nyeri Payudara Siklik) Nyeri payudara yang berkaitan dengan siklus menstruasi atau perubahan hormon wanita. Br J Cancer. 3 ). This article examines pain syndromes, including headache, back pain, osteoarthritis. This is the American ICD-10-CM version of N61. By using CKS, you agree to the licence set out in the CKS End User Licence Agreement. The prevalence of PMS symptoms among these patients with mastalgia is summarized in Table 1. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. 59 became effective on October 1, 2023. Introduction. Occurs monthly. The etiology of breast pain can be classified into three major categories: cyclic, noncyclical, and extra-mammary. Breast pain may be bilateral, unilateral or in part of one breast. 4 Mastodynia. 1 Description Intensity of mastalgia Timepoint before and after intervention Method of measurement Visual analogue scale (VAS) 2 Description Serum level of prolactin Timepoint before and after intervention. Introduction. Consider a diagnosis of cyclical breast pain when a woman with a normal breast exam describes pain that: Usually starts during the luteal phase of the cycle (within 2 weeks. The patient is requested to record her pain experience in terms of VLA score of “0” to “10. 10; and EPO plus vitamin E, p=0. Mastalgia is classified as cyclical, noncyclical, or extramammary. No TBW pattern correlated with any syndromes of breast pain or with any psychoneurotic profile, and most women did not conform to the traditional view that there is a premenstrual increase in TBW. . The review included. 7 times as likely as asymptomatic young women to have had a mammogram. Severe mastalgia was the dominant feature in 10 women with diffuse fibrocystic disease of the breast as judged by palpation and mammography and verified histologically. 48-55. 71 • ICD-10 code: N64. It is most common. This type of breast pain is. It accounts for approximately 50% of referrals to a specialised breast clinic, two-thirds of patients having cyclical and one-third experiencing noncyclical mastalgia, or pain arising from the chest wall deep to the. In a study including 1,150 patients that investigated the causes of mastalgia, the rates of cyclic and noncyclic mastalgia were found to be 61. Ultrasound, mammography,… Breast pain linked to the menstrual cycle is called cyclic breast pain or cyclic mastalgia. Untuk mengatasinya, biasanya dapat dengan pengompresan dengan kompres dingin maupun panas. Mastalgia. Breast pain that is associated with the menstrual cycle due to. Terasa lebih intens selama dua minggu menjelang awal periode menstruasi. Non. Materials and Methods Benign breast disease patients up to 35 years of age attending our surgery outpatient department from August. DOI: 10. Dysmenorrhea or painful menstruation is one of the most common problems of women. If you have cyclical breast pain, your GP may reassure you that what you’re experiencing is a normal part of your monthly cycle. mastalgia both cyclic and acyclic as 47. Sel dengan jumlah asam lemak tidak seimbang memengaruhi kepekaan jaringan pada payudara. breast pain is a common symptom experienced by up to two thirds of all women. Thirty-nine patients were randomized to Danazol arm and 42 in Centchroman arm. Breast pain (mastalgia) is a very common disorder experienced by women, and it was recognized as a relevant medical issue even before its first description, reported in the scientific literature in 1829. 10; and EPO plus vitamin E, p=0. However, non-cyclical pain isn’t always as easy to treat. Because of that, it’s more common in 20-to-50-year-old women — and it’s particularly common in women who are on the younger end of that range. Preece, A. Introduction. Richards, +1 author. Nine of 14 patients (64 per cent) with non-cyclical mastalgia obtained a good clinical response to drug therapy (over half responding to danazol alone); 19 underwent spontaneous remission, but there was a prolonged mean time to pain resolution of 27 months. Cyclic breast pain. The breast pain or mastalgia is the commonest presenting symptom to a breast clinic. Breast pain that is associated with the menstrual cycle due to hormonal variation often associated with breast swelling, tenderness, and lumpiness and generally bilateral in nature. 1). Cyclical mastalgia (CM) is the common symptoms in women, which is experienced many times in their life. CAUSES OF MASTALGIA. Research criteria for the diagnosis of cyclic mastalgia are (1) pain severity greater than 4. Obat-obatan lain yang dapat diberikan adalah danazol, tamoxifen, bromocriptine, suplemen. Cyclic breast pain: Cyclic mastalgia affects women in their 20s, 30s, or 40s, while they are still menstruating. Fibrocystic breasts have a lumpy, rope-like texture. Mastalgia and total body water. 0000000000001521 Open SDC Metrics Hyperplasia of the mammary glands (HMG) is a non-inflammatory and non-tumorous lesion. 5 ± 10. (P < 0. Most breast cancers do not cause pain. 391. 1A Although non-cyclical mastalgia has no such relationship, symptoms are often affected by hormonal. Last reviewed 1 Jan 2018. It had also been investigated as a treatment for cyclic and noncyclic. Effectiveness of Matricaria chamomilla (chamomile) extract on pain control of cyclic mastalgia: a double-blind randomised controlled trial. 1016/S1072-7515(97)00095-1 Corpus ID: 27768991; Cyclical mastalgia: prevalence and impact in an outpatient breast clinic sample. History will often reveal the temporal association of cyclical mastalgia with the menstrual cycle, but the best way to assess whether pain is cyclical is to ask the patient to complete a breast pain chart (Fig. 4 is a billable diagnosis code used to specify a medical diagnosis of mastodynia. A multicenter study randomized patients into four. Toggle Menu. 0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. 4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Breast pain refers to moderate to severe pain in one or both breasts lasting over a five-day period and faded after menopause. 7A may differ. Despite an absence of evidence suggesting that mastalgia alone is associated with breast cancer, it is still commonly referred to secondary care breast units — in one study it accounted. The pain which is specific to the breast is called true mastalgia and is divided into; Cyclical and Non-Cyclical Breast Pain. Noncyclic breast pain. However, non-cyclical pain isn’t always as easy to treat. 7. Cyclical mastalgia characterized by a swelling and minor discomfort lasting 1–4 days premenstrually is considered mild and the symptoms lasting for 5–14 days or more every month is considered moderate to severe. Mastodynia also known as Mastalgia or breast pain is a common complaint in females. If you have cyclical breast pain, your GP may reassure you that what you’re experiencing is a normal part of your monthly cycle. This study evaluates the benefits and side-effects of two drugs (tamoxifen or danazol) used randomly in women with severe cyclical mastalgia. This is the American ICD-10-CM version of N64. 8% and all of the patients with breast cancer in this group was postmenopausal. Most of them describe premenstrual mild cyclic mastalgia (CM) that lasts for 1 to 4 days as “normal” 8. What is mastalgia? Mastalgia is breast pain. 4 ICD-10 code description Cyclical breast pain can range intensity during menstruation Primary outcomes 1. 4 ICD-10 code description. Most RCTs have been conducted on Bromocriptine, Danazol, Tamoxifen and EPO, hence only these 4. Management of. % of lactation history, while family. Abscess in the breast also diagnosed in 5(5. Abstract: Cyclic mastalgia is one of the most prevalent disorders among fertile women. Factors associated with Mastalgia: 1. 59 - other international versions of ICD-10 N64. 71 is a billable medical code that can be used to indicate a diagnosis on a reimbursement claim, however, 611. Cyclic breast pain. 5%, respectively . 3 Approximately. 8%. Cyclical mastalgia consisted of a 2-month run-in phase for pain severity has been estimated by population-based surveys to screening and baseline assessments, a 4-month treat- affect from 22% to 41% of women [2, 4–6], with higher ment phase, and an optional 2-month follow-up phase. The pain may come from the breast. The pain may be constant or it. In the new pain chart, the lady records pain severity in the form of visual linear analogue scale score on every day of menstrual cycle. A total of 38 patients did not complain of any side. That the general practitioners considered early diagnosis to be important was made evident from a number of the results, and the evidence showing that long-term survival may be greater when delays are shorter is encouraging. Abstract Objective Different drugs are used to treat mastalgia, such as danazol and bromocriptine, and both are associated with side effects, due to which most of women. life, Health Care for Women International, DOI: 10. The pain was measured by visual analogue scale (VAS) of 0–10. Cyclical breast pain comes and goes regularly related to the menstrual cycle (monthly period). • Justification of ordering additional data:Cyclic breast pain: Cyclic mastalgia affects women in their 20s, 30s, or 40s, while they are still menstruating. Most breast cancers do not cause pain. However, diffuse bilateral pain is very common in women. , agnuside and. 200 mg-800 mg q 6 h. This type of pain usually occurs in both breasts. Lookup any ICD-10 diagnosis and procedure codes. Food and Drug Administration for treatment of severe activity-limiting mastalgia. 59 may differ. Health Problems (ICD-10) include the condition under benign mammary dysplasia (category N60) and sub-. Fibrocystic breasts are characterized by "lumpy" breasts associated with pain and tenderness that fluctuate with the menstrual cycle. Jenis Mastalgia. Cyclical is more common than noncyclical mastalgia; about two-thirds of women with mastalgia report cyclical symptoms with pain beginning in the week prior to menstruation (14, 15). Namun, ada beberapa faktor yang diduga menyebabkan seseorang mengalami kondisi mastalgia, yaitu: 1. [] found that more than half of the. o conduct a review of alternative therapy in the management of mastalgia. Cyclical breast pain (cyclical mastalgia) is a common symptom. The data were also analyzed with the separation test by Aickin, which showed a trend toward a reduction of cyclical mastalgia with vitamin E and EPO individually and in combination. 0 cm measured on a 10. (II-3 B) 3. Women with cyclical mastalgia have been found to have low levels of the metabolites of GLA in the plasma. (I A) 8. Browse for your desired term or condition, or search for a specific disease / condition. Diffuse bilateral pain may be caused by fibrocystic changes or, uncommonly, diffuse bilateral mastitis. 4: Mastodynia. 22. Results: Of the 236 patients, 10 women had cyclical breast pain, 116 had noncyclical, nonfocal breast pain, and 110 had noncyclical, focal breast pain. Pain can range from minor discomfort to severely incapacitating. Or it may come from somewhere else, such as nearby muscles or joints, and may be felt in the breast. In the last decade, case-control studies have reported that cyclical mastalgia could be. Cyclical breast pain is the condition experienced by two-thirds of patients with true mastalgia. In previous studies which were conducted to evaluate the effect of flaxseed on cyclic mastalgia, a specific amount of flaxseed powder (25–30 g/d) was administered for patients [6, 19, 20]. Granulomatous mastitis, left breast. The impact of this mastalgia on quality of life is often underestimated by the medical profess mastalgia is the commonest form of breast pain and has an obvious temporal relationship to the menstrual cycle, resolving at the menopause . This is the American ICD-10-CM version of N64. Asthma is a Mastalgia is considered the most common benign breast disorder in women during the fertile period by a prevalence rate of about 65% [1–3]. We have assessed the long-term course in patients with severe mastalgia by distributing a postal questionnaire to 212 patients previously studied in 1983 who had attended the mastalgia clinic at the University Hospital of Wales, Cardiff. The pain can range from minor discomfort to severely. Noncyclical mastalgia [4] Unilateral or bilateral breast pain, usually located over the costal cartilage. Only a small proportion of patients seek medical advice from their general practice team • breast pain can be cyclical and non-cyclical and is most common between the ages of 30 and 50 years. 7%) females had normal breast ultrasound from which 37(71. 10. Cyclic Mastalgia. Hershey Medical Center, 30. Mastalgia is the second most common breast symptom leading to medical evaluation in the primary care setting. Fibrocystic breast disease is the most common benign type of breast disease, diagnosed in millions of women worldwide. 1 - other international versions of ICD-10 R59. • Justification of ordering additional data:Tamoxifen at a dose of 10 mg / day for <6 months, continuous or limited to the luteal phase of the menstrual cycle, has shown an improvement in cyclic mastalgia in 70 to 90% and no clyclic mastalgia in 56% of cases 22. It often presents as diffuse bilateral pain but. improving cyclical mastalgia. 6 years, respectively. A topical preparation of this drug has recently been approved. About one third of women with breast pain have this type of pain. 0-cm visual analog scale and (2) pain duration of at least 7 days per month. 05). 4 ICD-10 code description Mastodynia Primary outcomes 1 Description severity of cyclic breast pain Timepoint at the begining of the study- at the end of first cycle of intervention- at the end of the second sycle of intervention Method of measurement visual analog scale 2 Description duration of the breast pain. 1 Approximately 60–70% of women suffer from moderate to severe breast pain in their lifetime among which 10–20% of the cases suffer from severe breast pain 2 who may need. Differential diagnosis. Breast pain before periods, known as cyclic mastalgia, affects as many as seven out of 10 females, with nearly a third experiencing extreme discomfort. This type of mastalgia is experienced 2–3 days before the menstrual period as gentle nodules in the breast [ 2 , 9 , 10 ]. This starter pack is exactly what every woman needs to bring her hormones back into balance!Cyclical mastalgia might last for more than 7 days in 11% of women . Tightness in breast tissue. 4. Up to 70% of. Table 4. 4 may differ. Mastalgia is classified as cyclical, ie. Next Term: Masters Allen Syndrome. Mean age at presentation was significantly greater in the musculoskeletal group (39·3 versus 33·9 years) with a shorter mean duration of pain. Representative examples of non-neoplastic disorders include fibrocystic disease, gynecomastia, and. bursitis due to use, overuse and pressure ( M70. These problems have been resolved in the new breast pain chart. The usual dose of Danazol for treatment of mastalgia is 100–400 mg per day. It is estimated that about 60 to 70% of all patients visiting breast clinic suffer from mastalgia. If the pain is associated with the menstrual cycle, the condition is referred to as cyclical mastalgia (cyclical breast pain). Certain hormonal factors underpin the function, evaluation, and treatment of this disease. Saat menjelang haid hingga menstruasi, tubuh wanita mengalami perubahan hormon. There are 2 main types of mastalgia: Cyclical breast pain. N64. Hence, finding an effective treatment that can alleviate the symptom is very important. Mastalgia is pain arising in the breast tissue. 0-cm visual analog scale and (2) pain duration of at least 7 days per month. 4) and treated with evening primrose. And it is important to note, that more often than not, the breast pain is not associated with breast cancer. Background: Mastalgia or breast pain common benign breast disorder in women in her. Am J Obstet Gynecol. A non-neoplastic or neoplastic disorder that affects the breast. Non-cyclical breast pain does not appear to be related to the menstrual cycle. Noncyclical mastalgia: • is usually unilateral, localised to one part of the breast; commonly the inner part of the breast or behind the nipple • is described as having a burning, stabbing, or throbbing quality • is more likely than cyclical mastalgia to beMastalgia is a medical term used for breast pain, one of the most common complaints among women of 15 to 40 years of age (child-bearing age). The link between cyclical mastalgia and breast cancer is very tenuous. Non-cyclical breast pain: • is not associated with the menstrual cycleInclusion criteria are women with cyclic mastalgia, pain score >4 and pain duration >5 days; exclude criteria are: Pregnancy, lactation, patient with psychological and somatic disease, history of breast cancer, hormone therapy since3 months , menopause and use of oral contraceptives. 4 ICD-10 code description Mastodynia Primary outcomes. Cyclic mastalgia: Visual analog scale: 94: B6 and evening primrose have the same therapeutic effects in the treatment of cyclical mastalgia: Alvandipour et al.